Question 1 · Hard
Three days after hip replacement, a patient is anxious and breathless. RR 30/min, HR 118/min, BP 128/76 mm Hg. ABG on room air: pH 7.51, PaCO2 4.0 kPa (30 mmHg), HCO3- 23 mmol/L, PaO2 8.0 kPa (60 mmHg). Which interpretation is most accurate?
- AMetabolic alkalosis with hypoxaemia; suspect vomiting
- BRespiratory alkalosis with normal oxygen; suspect anxiety
- CRespiratory acidosis, compensated; suspect opioid excess
- DRespiratory alkalosis with hypoxaemia; suspect pulmonary embolism
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Answer: D · Respiratory alkalosis with hypoxaemia; suspect pulmonary embolism
The pH is high and the PaCO2 is low with a normal bicarbonate, so this is an acute respiratory alkalosis from hyperventilation. The PaO2 of 8.0 kPa (60 mmHg) is clearly low, so the patient is not just anxious. Hypoxaemia, tachypnoea and tachycardia after joint surgery strongly suggest pulmonary embolism. The nurse gives oxygen, sits the patient up and reports urgently, without labelling the breathlessness as anxiety.
- A: The bicarbonate is normal, so the alkalosis is not metabolic.
- B: The PaO2 is low, so this is not a benign anxiety-driven picture.
- C: The pH is alkalotic and the PaCO2 low, the opposite of opioid-induced acidosis.