Question 1 · Medium
A 3-year-old with sickle cell disease has functional asplenia. Besides the routine schedule, which immunisation protection is most important for this child?
- AMonthly injections of normal immunoglobulin
- BA repeat dose of BCG vaccine every 5 years
- CA booster dose of rotavirus vaccine
- DExtra pneumococcal and meningococcal vaccines
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Answer: D · Extra pneumococcal and meningococcal vaccines
Children with sickle cell disease lose splenic function early in life, so they are at high risk of overwhelming infection with encapsulated bacteria such as Streptococcus pneumoniae and Neisseria meningitidis. They need extra pneumococcal and meningococcal vaccines, yearly influenza vaccine and usually penicillin prophylaxis. Parents must also be taught to seek care at once for any fever of 38.5°C or more. Sickle cell disease is common in the Gulf region.
- A: Routine immunoglobulin injections are not part of sickle cell care.
- B: BCG is not repeated and does not protect against encapsulated bacteria.
- C: Rotavirus vaccine is not given as a booster and does not prevent bacterial sepsis.