Question 1 · Medium
A 28-year-old man from Nagpur has had back pain for 3 months with evening fever and weight loss. There is tenderness over the thoracolumbar junction but no neurological deficit. X-ray shows narrowing of the T11-T12 disc space with erosion of the adjacent end plates. Which investigation best shows the extent of the disease?
- AContrast-enhanced MRI of the spine
- BTechnetium bone scan
- CConventional myelography
- DCT scan of the spine
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Answer: A · Contrast-enhanced MRI of the spine
Disc space narrowing with erosion of the adjacent vertebral end plates (the paradiscal pattern) in a young adult with constitutional symptoms suggests spinal tuberculosis. MRI with contrast is the investigation of choice: it shows marrow oedema early, the extent of vertebral and disc destruction, paravertebral and epidural abscesses, and compression of the cord. Tissue from CT-guided biopsy is sent for CBNAAT, culture and histology. Treatment is anti-tubercular therapy, with surgery for deficit or instability.
- B: A bone scan is non-specific and does not show abscess or cord compression.
- C: Myelography is invasive and outdated, replaced by MRI.
- D: CT shows bone destruction well but not marrow oedema, abscess spread or the cord.