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The question
A 22-year-old primigravida at 12 weeks is seen in a district hospital antenatal clinic: Hb 10.4 g/dL, MCV 64 fL, MCH 20 pg, RBC count 5.9 million/µL, RDW 13% (reference 11.5-14.5%), serum ferritin 88 ng/mL; the smear shows microcytes and target cells. Consider four statements: 1. The Mentzer index favours beta-thalassaemia trait. 2. A full course of therapeutic oral iron will correct her anaemia. 3. HPLC showing HbA2 above 3.5% would confirm the likely diagnosis. 4. Her husband should be screened for carrier status. Which statements are correct?
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