Question 1 · Hard
A 64-year-old man in the urology OPD asks why his doctor checks his prostate with a finger when he has had TURP for an enlarged gland five years ago. Consider these statements on the zones of the prostate: 1. The central zone forms most of the glandular tissue. 2. Benign hyperplasia arises mainly in the transition zone. 3. The central zone surrounds the ejaculatory ducts. 4. Most carcinomas arise in the peripheral zone, which can be felt per rectum. Which statements are correct?
- A3 and 4 only
- B2, 3 and 4 only
- C2 and 4 only
- D1, 3 and 4 only
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Answer: B · 2, 3 and 4 only
Statements 2, 3 and 4 are correct. In McNeal's zonal anatomy the peripheral zone, not the central zone, forms about 70% of the glandular prostate, the central zone (about a quarter) is a cone around the ejaculatory ducts, and the transition zone is a small area around the proximal urethra where hyperplasia begins. TURP removes transition-zone adenoma but leaves the peripheral zone, so cancer can still develop there and rectal examination and PSA remain useful. This is the counselling point for the patient.
- A: Leaves out statement 2: hyperplasia does begin in the transition zone.
- C: Leaves out statement 3: the central zone does surround the ejaculatory ducts.
- D: Includes statement 1, which is false: the peripheral zone is the largest, and leaves out statement 2.