Question 1 · Easy
Ca²⁺ released into the sarcoplasm starts muscle contraction by binding to
- Athe myosin head
- BG-actin
- Ctropomyosin
- Da subunit of troponin
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Answer: D · a subunit of troponin
Increased Ca²⁺ binds a subunit of troponin on the thin filaments. This removes the masking of the active sites on actin, so that myosin heads can bind there.
- A: The myosin head binds ATP and actin, not the Ca²⁺ that starts contraction.
- B: G-actin is the monomer of F-actin and holds the active sites, not the Ca²⁺ binding subunit.
- C: Tropomyosin runs along F-actin and is not the Ca²⁺-binding protein.
Remember this
Ca²⁺ binds troponin; the active sites on actin are unmasked and cross bridges can form.