Question 1 · Hard
A 31-year-old woman attends a new outpatient clinic for a routine check. Her creatinine is 76 µmol/L (0.86 mg/dL), the same as at another clinic of the same hospital a year ago. This time the report shows an eGFR (CKD-EPI 2021) of 68 mL/min/1.73 m², flagged low, compared with 93 last year. QC was in range, and the clinic doctor phones to query the result. The laboratory system shows her date of birth as 14/05/1945; the hospital's master patient record and her identity card show 14/05/1995. What should the laboratory do?
- ARecollect the sample to confirm her identity
- BCorrect the birth date and issue a corrected report
- CRerun the creatinine after recalibration
- DPhone the correct eGFR but leave the report
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Answer: B · Correct the birth date and issue a corrected report
The creatinine is unchanged and analytically sound, so the fall in eGFR must come from another input to the equation. CKD-EPI 2021 uses age and sex, and an age of 81 instead of 31 lowers the eGFR from about 93 to 68 for the same creatinine. The error arose when the patient was registered, a pre-analytical error that surfaced in a calculated result. The laboratory corrects the demographic record and issues a corrected report that is clearly marked as amended, with the original kept on file as ISO 15189 requires. It also informs the requesting doctor and logs the incident, so that other results registered with the wrong birth date are found and corrected.
- A: Her identity is not in doubt: the creatinine matches last year's, and only the birth date is wrong.
- C: QC was in range and the creatinine is consistent; only the age used in the calculation is wrong.
- D: A phoned result alone leaves a wrong eGFR in the permanent record.